The mechanistic principle (GHS release is somatostatin-feedback-governed) is sound and animal data on ipamorelin supports the pulsatile pattern, but ipamorelin-specific pulsatility evidence is limited to animal and in vitro models
Monitoring Physical Activity and Rest Movement is important during GLP-1 treatment, but pushing too hard when your energy is low can make fatigue worse
Beyond GLP1: modulating multiple nutrient-stimulated hormone pathways to reduce cardiovascular risk
Again, there is minimal research on microdosing, but proponents tout a few potential perks: Milder side effects: Ozempic, Zepbound, and other similar medications can cause gnarly gut issues (nausea, vomiting, diarrhea)
At InVia Fertility Specialists, we will start patients on progesterone supplementation the day after egg retrieval