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These include: A new or persistent lump or swelling in the neck, particularly in the thyroid region Progressive difficulty swallowing (dysphagia) or a sensation of pressure in the throat Persistent hoarseness or voice changes lasting more than three weeks Unexplained stridor (high-pitched breathing sound) Rapidly enlarging neck mass Patients experiencing any of these symptoms should contact their GP promptly for clinical assessment, in line with NICE guidance on suspected cancer referral (NG12)

Role of carnitine Carnitine supplementation (50 mg/kg per day) for 4 weeks was shown to correct both carnitine deficiency and hyperammonaemia in 14 VPA-treated patients [38]

Appetite control is important, but it is not the only factor involved in obesity

In this article, we explain what current evidence says about GLP-1 medications and eye health, discuss symptoms patients should be aware of, and review when it may be appropriate to seek an eye examination

The blood-brain barrier: Physiology and strategies for drug delivery