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This applies to both compounded and brand-name formulations

Nine shipments of medication labeled as Wegovy were also seized, as well as one shipment labeled as Mounjaro

Clinical studies, including the STEP 1 extension trial, have demonstrated that patients who discontinue GLP-1 receptor agonists often regain a significant portion of lost weightsometimes two-thirds or morewithin one year of stopping treatment

In trials to assess semaglutides effectiveness for reducing the risk of major cardiovascular events in adults, increases in total bilirubin greater than or equal to 3 times the upper limit of normal were seen in .3% of people taking Wegovy versus .2% of people taking the placebo

While this side effect seems disconcerting, its worth remembering that semaglutide and tirzepatide have overwhelmingly positive effects on heart health