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Dimethyl fumarate attenuates MSU-induced gouty arthritis by inhibiting NLRP3 inflammasome activation and oxidative stress

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It is suggested that high levels of DHEA have a beneficial effect on longevity and prevent several human pathologic conditions, including heart disease, diabetes, and chronic venous leg ulcers (Legrain and Girard, 2003

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For instance, prior studies have demonstrated that the activation of LXRs using synthetic agonists such as GW3965 and T0901317 suppresses Th17 cell differentiation in autoimmune diseases [29, 37, 38]