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In recent years, the therapeutic landscape in CKD management has expanded beyond traditional renin-angiotensin system (RAS) blockade to include sodium-glucose co-transporter 2 inhibitors (SGLT2is), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and non-steroidal mineralocorticoid receptor antagonists, such as finerenone [2, 7]

The decrease in systolic blood pressure is aseparate entity of GLp-1 effect unrelated to weight loss [1]