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Severe or persistent nausea may include symptoms like nausea that lasts a long time or gets worse, nausea that doesnt get better with home remedies, or nausea that interferes with daily activities like eating or drinking
doi: 10.1152/physrev.00018.2018 82 LiSLiuMCaoSLiuBLiDWangZet al
Corticosteroids promote: Fat redistribution , causing central (truncal) obesity and the characteristic "cushingoid" appearance with prolonged use Fluid retention , leading to weight gain that may not reflect true fat accumulation but can be discouraging Muscle protein breakdown , reducing lean body mass and potentially lowering metabolic rate Insulin resistance , making weight loss more difficult The magnitude of these effects is generally dose- and duration-dependent
In November 2013, Johnson & Johnson proposed a $2.5 billion settlement, plus an additional $3 billion for medical expenses, to cover about 8,000 DePuy ASR hip-implant claims filed by people injured by the metal-on-metal devices