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While the treatment with Ru(II)-OH or NP2 slightly elevated the ROS levels inside the hypoxic cancer cells, the treatment with NP4 showed a strong enhancement of ROS

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3.5 Cancers Currently, metabolic rewiring, which supports unrestricted proliferation and metastatic progression of cancer cells, is widely accepted to be an emerging hallmark of cancers (Petvri et al., 2020)

Clinically, BPC-157 is often used by athletes and patients recovering from surgery or chronic injuries due to its capacity to modulate the nitric oxide (NO) system, protect endothelial function, and reduce pro-inflammatory cytokines