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Ketamine was initially introduced as an anesthetic and analgesic for medical applications ( 5.1 Pharmacological effects 5.1.1 NMDAR antagonism Ketamine exerts its primary effects by acting as a noncompetitive antagonist of NMDARs and reducing glutamate-mediated excitatory neurotransmission (Zhou and Tajima, 2023)

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glp 1 and anxiety GLP-1 diabetes drugs could stop depression worsening, study finds | Drugs New in Comprehensive Physiology
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