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It is conceivable that some patients may have borderline slow gastric emptying and starting one of the GLP-1 agonists may precipitate a full-blown gastroparesis, Michael Camilleri, a Mayo gastroenterologist who has studied GLP-1 antagonists and gastric emptying, told CNN , noting elsewhere that Knight, Wright, and others might just be really unlucky. Per the report, the Federal Drug Administration (FDA) says its received reports of gastroparesis amongst users of GLP-1 drugs

The median recovery time was 23.00 3.80 months

Smaller, more frequent meals bypass this bottleneck

Gastrointestinal side effects The most frequently reported side effects associated with retatrutide treatment are gastrointestinal, including nausea, vomiting, diarrhea, and constipation