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Theres the gut-brain axis and enteric nervous system to relay signals, talk to the brain

Niacin (as Niacinamide)

This is a key reason why advanced oral formulations, like our BPC 157 Capsules, are developed with stability in mind

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4 The most influential primary work is a 2008 Gastroenterology study by Dalmasso and colleagues, which showed that KPV is transported into intestinal epithelial cells via the peptide transporter PepT1 and, once inside, reduces pro-inflammatory signaling