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[50] Symptomatic patients with IPF younger than 65 years of age and with a body mass index (BMI) 26 kg/m 2 should be referred for lung transplantation, but there are no clear data to guide the precise timing for LTx

Ovarian cysts Similar to endometriosis, ovarian cysts can lead to heavy, irregular periods, and spotting in between periods

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There is strong evidence that the endogenous and exogenous reactive oxygen and nitrogen species play a major role in the airway inflammation and are determinants of asthma severity[16] (Figure 1)

Coeliac disease, inflammatory bowel disease (Crohn's disease or ulcerative colitis), and chronic pancreatitis can all cause both B12 malabsorption and diarrhoea