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The ROS scavenging property of Sp was also replicated in the Drosophila models knocked-down for essential antioxidant enzymes catalase and glutathione peroxidase, where neuronal cells of 15 days AEL flies genetically expressing a redox biosensor, roGFP showed reduced fluorescence under Sp treatment (Fig

In this regard, GSTs that also possess glutathione peroxidase activities may play a crucial role in plant antioxidative defense by limiting the excessive spread of HR-associated cell death (Levine et al., 1994