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Since these biomarkers are trigged by a variety of environmental insults and produced by different biomolecular pathways, their selective and sensitive determination in urine would help broadly elucidate the pathogenesis of diseases mediated by environmental factors

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It is originally induced by a variety of biophysiological shocks or inflammatory mediators, and it serves as a protective response in the case of kidney injury

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Purohit M, Gupta G, Afzal O et al (2023) Janus kinase/signal transducers and activator of transcription (JAK/STAT) and its role in lung inflammatory disease