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By age 60, GHK-Cu levels in the body have fallen by roughly 60% a decline that correlates directly with the visible signs of skin aging: thinning, wrinkling, loss of firmness, slower healing

Although the pH of the contents within the stomach lumen of patients is typically highly acidic (pH1-3), the pH near the surface of the gastric epithelium measured in healthy patients is much more neutral (pH5-7) due to the presence of a protective mucous layer, bicarbonate secreted into this zone by epithelial cells, and the presence of mucosal blood flow, variables dependent on COX-1 mediated prostaglandin E2 production (Quigley & Turnberg, 1987)

ROS from glucocorticoids can cause many pathological conditions (65)