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Receptor Supersensitivity Blockade In the landmark 1997 Sikiric study published in Biological Psychiatry (PMID: 9547930), mice pretreated with haloperidol (a dopamine antagonist) developed behavioral supersensitivity to amphetamine challenge

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doi:10.1210/endo.142.12.8522 Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R

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In agreement, we observed that cellular GSH levels and the ratio of GSH/GSSG were increased in DMF treatment group (Fig