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In this respect, GPx seems to be a double-edged sword, playing opposite roles in regulating ROS and RNS ((35) and see (36) for a review of the opposing roles of GPx in oxidative stress)

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Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R

Beneficial effects of Astragalus membranaceus (fisch.) bunge extract in controlling inflammatory response and preventing asthma features

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