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Ways to support phase II estrogen detoxification The phase II estrogen detoxification pathways are important for converting reactive phase I metabolites into water-soluble, inactive phase II estrogen metabolites that can no longer damage DNA

Plant-based diets Vitamin B-12 is found almost exclusively in animal products like meat, poultry, dairy, fish, and eggs

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If homocysteine is high, the many factors listed in Table 3 need to be addressed as well as supplementation with the activated forms of B 6, folate (not folic acid) and B 12