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Patients with nevi showing dermoscopic findings suggestive of atypical nevi or suspicious changes or with histopathological findings of atypical nevi or malignant changes, nevi over nail bed, genitals and mucosa, and patients with history of keloid formation were excluded from the study

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It also stimulates nitric oxide synthase, improving local blood flow, and modulates the FAK-paxillin pathway to enhance fibroblast migration for collagen deposition

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When the levels drop, the cell dies