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For instance, a large network meta-analysis showed that SGLT-2 inhibitors reduced hospitalization for HF and renal composite outcome more than GLP-1RA [15], and that in patients with cardiovascular disease, SGLT-2 inhibitors show significant reduction in both heart failure (HF) hospitalizations and mortality for patients with HF and reduced ejection fraction [16]

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In this regard, through Woods lamp examination method, melasma has been categorized as epidermal, dermal, mixed, and intermediate types in which the epidermal melasma is the most common type among patients with melasma lesions

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