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Endogenous GLP-1 is produced both by enteroendocrine cells in the gut, and preproglucagon (PPG) neurons in the brain, which are the defining populations of the peripheral and central GLP-1 systems, respectively 3,4

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5B) was most likely due to its flux into NADP(H) production, where NADPH is required by xenobiotic detoxification enzymes for the metabolism of Dox

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