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In a mouse model of AD, long-term administration of ketone esters lessened amyloid -peptide and hyperphosphorylated tau deposition, which decreased levels of anxiety and improved cognition (140)

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1):S517 ORIGIN Trial Investigators, Gerstein HC, Bosch J, Dagenais GR, Daz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydn LE, Yusuf S (2012) Basal insulin and cardiovascular and other outcomes in dysglycemia

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