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Global GLP-1 receptor deficiency consistently results in attenuated glucose excursions during oral glucose tolerance tests, accompanied by reduced circulating insulin levels.39 Conversely, GLP-1 receptor knockout mice exhibited elevated blood glucose levels in intraperitoneal glucose tolerance tests,40 indicating that GLP-1 receptor is essential for maintaining normoglycemia

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doi.org/10.3390/ijms19071987 Seiwerth, S., et al

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