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Individuals who are pregnant, breastfeeding, or planning to become pregnant, unless approved by a healthcare provider

The most important and most frequently used indication for DPP-4 inhibitors is their add-on use in patients who are not sufficiently controlled on metformin monotherapy (12, 1719, 21, 22)

Stop taking your medication and call 911 or go to the emergency department if you experience any of the following: Severe, persistent stomach pain that may radiate to your back (especially with vomiting), as this could indicate pancreatitis

Patients with a history of migraine, tension-type headaches, or medication-related headaches may be more vulnerable

Co-localization studies revealed that many of the DNA damage sites that are occupied by -H2AX did not co-localize with pNPM1 to efficiently repair all the damaged sites, which could in turn lead to tumor cell death