With over a decade of experience in internal and preventive medicine, Dr
In general, every 24kcal/day Reduction in energy intake results in 1kg loss over time with half being lost by 1 year
While exact dosing varies, the microdosing GLP-1 approach generally includes: Starting with a lower dose than standard treatment (such as Ozempic or Mounjaro) to allow the body to adjust Gradual adjustments over time based on tolerance, appetite changes, and results Monitoring appetite, digestion, and energy levels to guide dosing decisions Tracking weight and overall progress to ensure the approach is effective Because GLP-1 medications affect metabolism and blood sugar, this approach should always be individualized
CLINICAL TRIALS WITH CAGRILINTIDE Two clinical trials have investigated the efficacy of cagrilintide in comparison to the GLP-1 agonists liraglutide and semaglutide (Fig
FDA reviewers cited weak clinical evidence, substance-characterization concerns, differences between studied and proposed administration routes, and the availability of approved treatments for conditions discussed during the review
