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The molecule was advanced into clinical development by the Croatian pharmaceutical company Pliva under the designations PL-10, PLD-116, and PL 14736 for inflammatory bowel disease research

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Concentration and absorption challenges Copper peptides face a fundamental delivery problem

long-term use associated with osteoporosis, adrenal suppression (code separately) Immunomodulators: Azathioprine (AZA), 6-mercaptopurine (6-MP), methotrexate for maintenance of remission

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