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This pattern aligns with our previous work in DIO male mice using the same semaglutide dose, where we observed an approximately 20% reduction in EDL force after one week of the treatment that recovered by week three, despite no changes in fiber CSA or fiber-type composition (14)

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Adverse Events: Frequency, Severity, and Management Strategies Most common side effects are gastrointestinal: nausea affects 2550% of users, constipation 2030%, and vomiting 515% depending on dose and individual sensitivity