Most patients notice appetite suppression within the first 1-2 weeks
On one hand, it can degrade intestinal mucin glycoproteins by enzymes (such as glycoside hydrolases, proteases, sulfatases, and sialidases) to produce SCFAs, acetates, propionates, and 1,2-propanediol, as well as succinates and sulfates, promoting mucin turnover and thickening, thereby enhancing intestinal barrier function and reducing the permeability of gut microbiota products
Previous bariatric surgery Patients with any history of gastric bypass, sleeve gastrectomy, or other bariatric procedures require lifelong b12 monitoring and supplementation
Key Background Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of drugs used to treat diabetes and weight loss by interacting with the hunger part of the brain to suppress the appetite, and lowering blood sugar and A1C
Without nutritional guidance, patients may inadvertently develop nutrient deficiencies, lose muscle mass due to inadequate protein intake, or fail to establish the eating patterns needed for long-term weight maintenance