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doi: 10.1007/PL00005896 76 YoonM-S

Nat Rev Drug Discov 9(8):628642

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In the connection between mitochondrial metabolism and aging, prior work reported decreased levels of LAC in subjects with Alzheimers disease (AD) as compared to cognitively healthy controls, with intermediate levels in subjects with subjective memory complaint or mild cognitive impairment [64]

Results: A total of 10 RCT studies, 1239 T2DM patients were included for analysis, including eight studies of l-carnitine, one study of acetyl-l-carnitine, and one study of propionyl-l-carnitine