This work demonstrated that GLP-1RA treatment was associated with a significant 29% reduction in MALOs compared to non-use (IRR: 0.71, 95%CI: 0.57-0.88, P = 0.003) over a median follow-up of approximately 70,045 patient-years
Notably, all participants started with very high ICP (mean ~ 30.6 cmCSF), so a 56 cmCSF reduction was felt to be clinically meaningful (roughly 1520% reduction)
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When administered in the correct dosage, DSIP is considered safe and effective for improving sleep quality and overall well-being
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