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Of note, enzymatic GSH, GSSG, and GSH:GSSG measurements corresponded well with measures using a high-performance liquid chromatography system (Supplemental Figure 1)

By employing human-induced pluripotent stem cell (iPSC)-derived neurons (iNeurons), we demonstrate that DUB inhibition can recapitulate a significant fraction of age-related ubiquitylated signatures identified in the mouse brains

Impact of Glutamate on Immune Cell Functions Despite dietary glutamate being almost completely used in intestinal tissues, studies investigating the effects of glutamate on intestinal immune cells are lacking

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Reduced serum IgE levels and decreased extent of goblet cell metaplasia and inflammatory cell infiltration of the lamina propria were observed [196]