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Selective proteolysis by matrix metalloproteinases of photo-oxidised dermal extracellular matrix proteins

Indicatively, there is activation of the VEGFR2-Akt-eNOS signaling pathway without the need for other known ligands or shear stress and evidenced control of vasomotor tone by the activation of the Src-Caveolin-1-eNOS pathway

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this result is similar to the findings shown in Figure 1e, right column ( bars 8 and 9 , missing the wash-out step)