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The early weeks involve neurochemical adjustment and caloric restriction effects

Sequential designs suggest CBT's role for nonresponders to behavioral and/or pharmacological weight loss treatment, while for responders continued medication may be helpful

Related to physiology, GSH is imported and degraded as a sulfur source in Francisella species 20,21,22 , while Streptococcus species and Hemophilus influenzae rely on host GSH to defend against oxidative stress 23,24

NAC has been used in medical settings for decades, primarily as a treatment for acetaminophen overdose and as a mucolytic agent to break down mucus in respiratory conditions

Limitations of this study include a small sample population of healthy older adults with high BMI in order to ensure safety