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Taken together, the findings in this study point to the use of P-gp-induced ROS as a mechanism to limit the rise of drug efflux dependent resistant tumor cells pre- or post-treatment with chemotherapeutic drugs

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Furthermore, the O2- also gets converted into stable form H2O2 by the mitochondrial form of SOD (Mn- SOD)

Riechmann JL,Ratcliffe OJ.A genomic perspective on plant transcription factors.Current Opinion in Plant Biology.2000;3(5):423-434 218