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J Appl Phycol 32:15971606

However, Tirzepatide is a dual GIP/GLP-1 receptor co-agonist

Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, et al

Combine this with a genetic variant for an enzyme called diamine oxidase (DAO), the main enzyme responsible for metabolizing ingested histamine, and the result is high histamine which can lead to headaches

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