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Despite these effects, no notable changes were observed in reproductive indices or the gross morphology and histopathology of the ovaries, uterus, or vagina

doi: 10.1111/joim.12251

These cells are characterized by the expression of macrophage-associated markers, such as CD206, CD169, CD163, CD36, and LYVE1, and exhibit a distinct transcriptional signature from parenchymal microglia, characterized by the expression of genes, including Ms4a7 , Ms4a6c , Tgfbi , and Lyz2 [126,127,128]

Researchers may not be able to conclude that excessive cell death induced by ferroptosis is associated with pathogenic processes based only on the preventive effect of ferrostatin-1 or liproxstatin-1 on cell death 21 , as these compounds are essentially antioxidants and may inhibit other ROS-dependent forms of cell death, such as necroptosis 46

However, preserving final remaining function still valuable for quality of life