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Success rates ranged from 100% (6 of 6) 232 to zero (4 of 4 failed)

NEJM SURPASS-2 (Tirzepatide vs Semaglutide)

Humans have far fewer GLP-1 receptors on their thyroid C-cells than rats, and so far no evidence of increased thyroid cancer has been confirmed in humans

Because semaglutide can cause muscle loss alongside fat loss, strength training serves double duty: it preserves the muscle mass that drives venous return AND it provides the movement needed to keep blood flowing

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