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A pH-responsive metal-organic framework for the co-delivery of HIF-2 siRNA and curcumin for enhanced therapy of osteoarthritis

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This analysis revealed that the unfolded polypeptides (proteins or synthetic polypeptides) have high R g values and are invariantly characterized by the lack of a peak in Kratky plot

In the chronic toxicity experiment, L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs