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1 Dual agonism of GIP and GLP-1 receptors is a promising new approach currently in clinical development for the treatment of diabetes, obesity, and associated complications [1] The incretin effect defines the main physiological role of GIP and GLP-1 GIP and GLP-1 increase insulin secretion following nutrient-induced secretion from the gut (incretin effect): There is a stronger insulin secretion response to oral compared to 'isoglycemic' intravenous glucose administration due to secretion and action of incretin hormones

Retatrutide (GLP-3) is a next-generation triple receptor agonist that targets GLP-1, GIP, and glucagon receptors simultaneously

Glow Blend is a laboratory peptide mixture containing TB-500 (10mg), BPC-157 (10mg), and GHK-Cu (50mg), totaling 70mg

Macrophage-derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection