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Available now (UK): Rybelsus (oral semaglutide) for type 2 diabetes (not a UKlicensed weightloss tablet)

doi: 10.1002/bjs.4916 Wilson LJ, Ma M.S W, Hirschowitz BI (1999) Association of obesity with hiatal hernia and esophagitis

Cejkova J, Ardan T, Simonova Z, Cejka C, Malec J, Jirsova K, et al

Conversely, CPP-CAND targets FOXO4, which is explicitly expressed in senescent cells, providing a senescent cell-specific target

While the long-term use of semaglutide appears safe for the general population, including those with diabetes and obesity, its long-term safety profile in hypothyroid patients requires more specific research