The upregulated metabolites included Bhos#36, armillaripin, -Glutamylcysteine, 19-oxodesacetylcinobuf-agin, chlorophyll, WithaferinA, JP83, L-proline, trans-cinnamic acid (TCA), indoleacrylic acid, ammonia aspartate,[(2s,4R,5R,6R,14S,16R)-14-hydroxy-7,11-dimethyl-6-(2-OXOPYRAN-4-Y-L)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16] octadecan-5-yl] acetate, PGP (22:6(5Z, 8E, 1-0Z, 13Z, 15E, 19Z) 2OH (7s, 17S)/20:4(8Z, 11Z, 14Z, 17Z), PS (21:0/18:0), 3-(4-Met-hyl-3-pentenyl)thiophene (Table 1)
Recently, we reported that Syn functions as histone chaperone, binds with high-affinity and specificity to assembled histone H2a-H2b dimer and H3-H4 tetramer 73
Dihexa may serve as a qualitative reference compound in structural verification workflows involving LC-MS, HPLC and NMR techniques
They are also rich in cysteine, an amino acid that promotes glutathione production
Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway