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Review on plant antimicrobials: a mechanistic viewpoint

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Actual bacterial fragments are getting into your brain and triggering inflammation there Inflammation is upstream of basically every major disease: type 2 diabetes, cancer, Alzheimers, frailty

The energy-deprived state observed in hypoxic conditions can be compensated by the degradation of certain molecules containing high-energy phosphate bonds, leading to increased levels of adenosine, which is subsequently degraded to hypoxanthine, xanthine, and ultimately uric acid 49

The serum-induced increase in p53 ubiquitination was blocked by a PI3K inhibitor, suggesting that phosphorylated Akt enhances the ubiquitination-promoting function of MDM2, determining reduction of the p53 protein