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(2020) Comparison of sublingual and intramuscular administration of vitamin B12 for the treatment of vitamin B12 deficiency in children

However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision

Some of the risks can be serious, such as fluid buildup in the lungs or a blood clot

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

This is to quickly fix the deficiency