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Clinical trials involving positron emission tomography (PET) with translocator protein expressed by activated microglia (TSPO) have demonstrated that seizures, temporal lobe epilepsy, frontal lobe epilepsy, and focal cortical dysplasia are associated with neuroinflammation, and their acute onset leads to chronic neuroinflammation and exacerbates its deterioration (145)

Methylation of B3GAT2 (beta-1,3-glucuronyltransferase 2), CCNA1 , TFPI2 , TWIST1 , VIM , and ZNF793 (Zinc finger protein 793) can be confirmed using MethyLight PCR and Cytosponge, a non-endoscopic tool ( TFPI2 has shown promise as a diagnostic biomarker for BE