Free radicals disrupt collagens and elastin fibers that prominently help in maintaining skin texture
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In other words, its not just about what gets absorbed its about what gets triggered
Evidence from RCTs for the use of B12 in other types of neuropathies is scarce, although non-randomised/uncontrolled studies have shown some benefits
Release of proangiogenic factors and increased hypoxia in response to vascularization blockade can lead to recruitment of endothelial progenitor cells (EPC) from the bone marrow, which contribute to tumor vascularization and have been linked to development of resistance to anti-VEGF therapy [303]