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On Thursday, Eli Lilly, the maker of tirzepatide, issued a warning to the public

One meal, one day, or one detour doesnt undo your progress

But you still need to eat in a calorie deficit for weight loss, choose nutrient-dense whole foods most of the time, get regular physical activity including both cardio and strength training, get adequate sleep since poor sleep disrupts appetite hormones, manage stress as chronic stress elevates cortisol and promotes fat storage, and address emotional or behavioral eating patterns

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The bottom line Yes, semaglutide does expire