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The mechanism is structural

doi: 10.1146/annurev-physiol-021115-105238 82 CardenasPACooperPJCoxMJChicoMAriasCMoffattMFet al

People who have very little weight loss may still get real benefit for treating cardiovascular and liver disease, sleep apnea, and a range of inflammatory and neurological diseases

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Infection Any IV carries an infection risk if hygiene is poor