phospholipid hydroperoxide glutathione peroxidase AffiELISA® Rat peroxidase, nuclear ELISA [Gpx4] Phospholipid hydroperoxide glutathione peroxidase |

Discovered in 1973, this tripeptide has accumulated over 40 years of research demonstrating its regenerative properties

Due to the low structural similarity to glutamine, BPTES has low off-target properties and decreased side effects (Xiang et al., 2015

doi: 10.1371/journal.pone.0026552 123 GongSChenYMengFZhangYWuHWuF

In the context of cancer prevention, HO-1 has been shown to be cytoprotective and to potently prevent inflammation

However, as a respond, breast cancer cells increased the expression of Nrf2 that led to the activation of ARE and increased transcription of genes associated with anti-oxidation and multidrug resistance transporters, thus increasing the survival from oxidative damage induced by tamoxifen [109]