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However, levels decline with age, illness, and environmental exposure

Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells

Furthermore, MHC class II-dependent microglia antigen presentation seems dispensable for disease establishment and progression, as observed in EAE and cuprizone models (145), corroborating to a less prominent role of these cells, at least, in triggering inflammation