Degrees of freedom were accounted for during all post-hoc testing

swelling of your face, lips, tongue, or throat Abnormal heart rhythm: chest pounding, irregular heart beat, chest pain, short of breath, feeling faint or lightheaded Heart attack Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness or twitching, uncoordinated movement, distress, hallucinations Effects of other drugs, drug classes and over-the-counter products on Zofran The following medications may interact with Zofran: Serotonergic Drugs: Serotonin syndrome (including altered mental status, autonomic instability, and neuromuscular symptoms) has been described following the concomitant use of 5-HT3 receptor antagonists and other serotonergic drugs including selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs) Drugs Affecting Cytochrome P-450 Enzymes: In patients treated with potent inducers of CYP3A4 (i.e., phenytoin, carbamazepine, and rifampin), the clearance of ondansetron was significantly increased and ondansetron blood concentrations were decreased

I.Il'inaE
Patients considering TTh should be counseled on disease modification and the possibility of discontinuing TTh in the future, before initiation of therapy , and the alternatives discussed in this review also should be considered first in appropriate candidates
Hepatol Commun 2017