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Contact your healthcare provider if you experience: Severe or ongoing side effects Rapid weight regain after stopping Blood sugar problems (especially if you have diabetes) Depression or mood changes related to weight regain Thoughts of disordered eating behaviors Heres What I Really Want You to Know Listen, Ive had this conversation with thousands of patients over the years, and heres what I always tell them: there is absolutely zero shame in needing long-term medication for weight management